University of Southern California
University of Southern California
Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy
Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy
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Sensory Adapted Dental Environments to Enhance Oral Care for Children (SADE-2)

Principal Investigator: Sharon Cermak, EdD, OTR/L, FAOTA
Co-Investigator: Leah Stein Duker, PhD, OTR/L
Co-Investigator: José Polido, DDS
Co-Investigator: Marian Williams, PhD
Co-Investigator: Michael Dawson, PhD
Co-Investigator: Christianne Lane, PhD
Co-Investigator: Joel Hay, PhD

Project Period: 5/1/15 – 4/30/20
Funding Source: National Institute of Dental and Craniofacial Research
Award Number: 1 U01 DE024978-01
Anticipated Award: $3,139,788

The SADE-2 study is a randomized clinical trial of 184 ethnically diverse children with autism spectrum disorder (ASD). We are investigating the efficacy of a sensory adapted dental environment (SADE) compared to a regular dental environment (RDE) to decrease children’s physiological anxiety, distress behavior, perception of pain, and sensory discomfort during a dental cleaning. If successful, this intervention has the potential to revolutionize clinic-based dental care for the growing population of children with ASD. It is an innovative solution that will enable dentists to more readily perform standard clinic-based procedures for children with ASD.

For more information, visit the SADE-2 study site.