University of Southern California
University of Southern California
Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy
Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy
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Cheryl Vigen PhD

Cheryl Vigen PhD

Associate Professor of Research

Room: CHP 101J
(323) 442-2749
.(JavaScript must be enabled to view this email address)

Biography

Cheryl Vigen is an Associate Professor of Research in the USC Division of Occupational Science and Occupational Therapy, and a member of the SC CTSI Biostatistics, Epidemiology, and Research Design (BERD) Core in the USC Division of Biostatistics and Epidemiology. With advanced degrees in epidemiology, biostatistics and mathematics she has served as biostatistician on several clinical trials and has experience in a wide variety of projects involving epidemiology, statistics, and data management. These projects have covered medical areas as diverse as cancer, HIV, cardiovascular disease, ophthalmology, dentistry, and hepatology.  In addition to managing and analyzing data, she works closely with OSOT study teams to monitor and assess the progress of the studies and to trouble-shoot problems and concerns.  She has been particularly involved in the Resilient, Empowered, Active Living (REAL) with Diabetes Study, the Pressure Ulcer Prevention Study (PUPS), and the Well Elderly Study, all major clinical trials conducted by USC Chan OSOT.  Dr. Vigen is available to consult with other faculty, staff and students regarding study design, data management and statistical analysis.

Education

Doctor of Philosophy (PhD) in Epidemiology
2007 | University of Southern California

Master of Science (MS) in Biostatistics
2003 | University of Southern California

Master of Science (MS) in Mathematics
1979 | University of Illinois at Chicago

Bachelor of Arts (BA) in Mathematics
1977 | University of California, San Diego

Publications

2019

Journal Articles

Pyatak, E. A., Carlson, M., Vigen, C. L., Blanchard, J., Schepens Niemiec, S., Sideris, J., & Baranek, G. T. (2019). Contextualizing the positive effects of the Well Elderly 2 trial: A response to Schelly and Ohl (2019). American Journal of Occupational Therapy, 73, 7306205100. https://doi.org/10.5014/ajot.2019.038752 Show abstract

Lee, H. Y., Vigen, C., Zwaigenbaum, L., Bryson, S., Smith, I., Brian, J., Watson, L. R., Crais, E. R., Turner-Brown, L., Reznick, J. S., & Baranek, G. T. (2019). The performance of the First Year Inventory (FYI) screening on a sample of high-risk 12-month-olds diagnosed with autism spectrum disorder (ASD) at 36 months. Journal of Autism and Developmental Disorders. Advance online publication. https://doi.org/10.1007/s10803-019-04208-5 Show abstract

Pyatak, E., King, M., Vigen, C. L., Salazar, E., Díaz, J., Schepens Niemiec, S. L., Blanchard, J., Jordan, K., Banerjee, J., & Shukla, J. (2019). Addressing diabetes in primary care: Hybrid effectiveness–implementation study of Lifestyle Redesign® occupational therapy. American Journal of Occupational Therapy, 73(5), 7305185020p1-7305185020p12. https://doi.org/10.5014/ajot.2019.037317 Show abstract

Carandang, K., Vigen, C. L., Ortiz, E., & Pyatak, E. A. (2019). Re-conceptualizing functional status through experiences of young adults with inflammatory arthritis. Rheumatology International. Advance online publication. https://doi.org/10.1007/s00296-019-04368-8 Show abstract

Carlson, M., Vigen, C. L., Rubayi, S., Blanche, E. I., Blanchard, J., Atkins, M., Bates-Jensen, B., Garber, S. L., Pyatak, E. A., Díaz, J., Floríndez, L. I., Hay, J. W., Mallinson, T., Unger, J. B., Azen, S. P., Scott, M., Cogan, A., & Clark, F. (2019). Lifestyle intervention for adults with spinal cord injury: Results of the USC-RLANRC Pressure Ulcer Prevention Study. Journal of Spinal Cord Medicine, 42(1), 2–19. https://doi.org/10.1080/10790268.2017.1313931 Show abstract

Schepens Niemiec, S. L., Blanchard, J., Vigen, C. L., Martínez, J., Guzmán, L., Fluke, M., & Carlson, M. (2019). A pilot study of the ¡Vivir Mi Vida! lifestyle intervention for rural-dwelling, late-midlife Latinos: Study design and protocol. OTJR: Occupation, Participation and Health, 39(1), 5-13. https://doi.org/10.1177/1539449218762728 Show abstract

Sleight, A. G., Cogan, A. M., Hill, V. A., Pyatak, E. A., Díaz, J., Floríndez, L. I., Blanchard, J., Vigen, C., Garber, S. L., & Clark, F. A. (2019). Factors protecting against pressure injuries in medically underserved adults with spinal cord injury: A qualitative study. Topics in Spinal Cord Injury Rehabilitation, 25(1), 31-40. https://doi.org/10.1310/sci2501-31 Show abstract

2018

Journal Articles

Vigen, C. L., Carandang, K., Blanchard, J., Sequeira, P. A., Wood, J. R., Spruijt-Metz, D., Whittemore, R., Peters, A. L., & Pyatak, E. A. (2018). Psychosocial and behavioral correlates of A1C and quality of life among young adults with diabetes. The Diabetes Educator, 44(6), 489–500. https://doi.org/10.1177/0145721718804170 Show abstract

Schepens Niemiec, S. L., Blanchard, J., Vigen, C., Martínez, J., Guzmán, L., Concha, A., Fluke, M., & Carlson, M. (2018). Evaluation of ¡Vivir Mi Vida! to improve health and wellness of rural-dwelling, late middle-aged Latino adults: Results of a feasibility and pilot study of a lifestyle intervention. Primary Health Care Research & Development, 19, 448-463. https://doi.org/10.1017/S1463423617000901 Show abstract

Pyatak, E. A., Carandang, K., Vigen, C. L., Blanchard, J., Díaz, J., Concha-Chavez, A., Sequeira, P. A., Wood, J. R., Whittemore, R., Spruijt-Metz, D., & Peters, A. L. (2018). Occupational therapy intervention improves glycemic control and quality of life among young adults with diabetes: The Resilient, Empowered, Active Living With Diabetes (REAL Diabetes) randomized controlled trial. Diabetes Care, 41(4), 696-704. https://doi.org/10.2337/dc17-1634 Show abstract

Juang, C., Knight, B. G., Carlson, M., Schepens Niemiec, S. L., Vigen, C., & Clark, F. A. (2018). Understanding the mechanisms of change in a lifestyle intervention for older adults. The Gerontologist, 58(2), 353–361. https://doi.org/10.1093/geront/gnw152 Show abstract

Weigensberg, M. J., Vigen, C., Sequeira, P., Spruijt-Metz, D., Juarez, M., Florindez, D., Provisor, J., Peters, A., & Pyatak, E. A. (2018). Diabetes Empowerment Council: Integrative Pilot Intervention for Transitioning Young Adults With Type 1 Diabetes. Global Advances in Health and Medicine. Advance online publication. https://doi.org/10.1177/2164956118761808 Show abstract

2017

Journal Articles

Wu, A. H., Vigen, C. L., Butler, L. M., & Tseng, C.-C. (2017). Metabolic conditions and breast cancer risk among Los Angeles County Filipina Americans compared with Chinese and Japanese Americans. International Journal of Cancer, 141(12), 2450-2461. https://doi.org/10.1002/ijc.31018 Show abstract

Pyatak, E. A., Sequeira, P. A., Vigen, C. L., Weigensberg, M. J., Wood, J. R., Montoya, L., Ruelas, V., & Peters, A. L. (2017). Clinical and psychosocial outcomes of a structured transition program among young adults with type 1 diabetes. Journal of Adolescent Health, 60(2), 212-218. https://doi.org/10.1016/j.jadohealth.2016.09.004 Show abstract

Pyatak, E. A., Carandang, K., Vigen, C., Blanchard, J., Sequeira, P. A., Wood, J. R., Spruijt-Metz, D., Whittemore, R., & Peters, A. L. (2017). Resilient, Empowered, Active Living with Diabetes (REAL Diabetes) study: Methodology and baseline characteristics of a randomized controlled trial evaluating an occupation-based diabetes management intervention for young adults. Contemporary Clinical Trials, 54, 8-17. https://doi.org/10.1016/j.cct.2016.12.025 Show abstract

2016

Journal Articles

Wu, A. H., Vigen, C. L., Lee, E., Tseng, C.-C., & Butler, L. M. (2016). Traditional breast cancer risk factors in Filipina Americans compared with Chinese and Japanese Americans in Los Angeles County. Cancer Epidemiology, Biomarkers & Prevention, 25(12), 1572–1586. https://doi.org/10.1158/1055-9965.EPI-16-0203 Show abstract

Carandang, K., Pyatak, E. A., & Vigen, C. P. (2016). Systematic review of educational interventions for rheumatoid arthritis. American Journal of Occupational Therapy, 70(6), 7006290020p1-7006290020p12. https://doi.org/10.5014/ajot.2016.021386 Show abstract

Sposto, R., Keegan, T. H., Vigen, C. L., Kwan, M. L., Bernstein, L., John, E. M., Cheng, I., Yang, J., Koo, J., Kurian, A. W., Caan, B. J., Lu, Y., Monroe, K. R., Shariff-Marco, S., Gomez, S. L., & Wu, A. H. (2016). The effect of patient and contextual characteristics on racial/ethnic disparity in breast cancer mortality. Cancer Epidemiology, Biomarkers & Prevention, 25(7), 1064-1072. https://doi.org/10.1158/1055-9965.EPI-15-1326 Show abstract

Leland, N. E., Fogelberg, D., Sleight, A., Mallinson, T., Vigen, C., Blanchard, J., Carlson, M., & Clark, F. (2016). Napping and nighttime sleep: Findings from an occupation-based intervention. American Journal of Occupational Therapy, 70(4), 7004270010p1-7. https://doi.org/10.5014/ajot.2016.017657 Show abstract

Cogan, A. M., Blanchard, J., Garber, S. L., Vigen, C. L., Carlson, M., & Clark, F. A. (2016). Systematic review of behavioral and educational interventions to prevent pressure ulcers in adults with spinal cord injury. Clinical Rehabilitation, 31(7), 871-880. https://doi.org/10.1177/0269215516660855 Show abstract

Vigen, C. L., Kwan, M. L., John, E. M., Gomez, S. L., Keegan, T. H., Lu, Y., Shariff-Marco, S., Monroe, K. R., Kurian, A. W., Cheng, I., Caan, B. J., Lee, V. S., Roh, J. M., Bernstein, L., Sposto, R., & Wu, A. H. (2016). Validation of self-reported comorbidity status of breast cancer patients with medical records: the California Breast Cancer Survivorship Consortium. Cancer Causes & Control, 27(3), 391-401. https://doi.org/10.1007/s10552-016-0715-8 Show abstract

2015

Books

Clark, F. A., Blanchard, J., Sleight, A., Cogan, A., Eallonardo, L., Floríndez, L., Gleason, S., Heymann, R., Hill, V., Holden, A., Jackson, J. M., Mandel, D. R., Murphy, M., Proffitt, R., Niemiec, S. S., Vigen, C., & Zemke, R. (2015). Lifestyle redesign: The intervention tested in the USC Well Elderly Studies (2nd ed.). Bethesda, MD: American Occupational Therapy Association. Full text Show abstract

Journal Articles

Shariff-Marco, S., Yang, J., John, E. M., Kurian, A. W., Cheng, I., Leung, R., Koo, J., Monroe, K. R., Henderson, B. E., Bernstein, L., Lu, Y., Kwan, M. L., Sposto, R., Vigen, C. L., Wu, A. H., Keegan, T. H., & Gomez, S. L. (2015). Intersection of race/ethnicity and socioeconomic status in mortality after breast cancer. Journal of Community Health, 40(6), 1287-1299. https://doi.org/10.1007/s10900-015-0052-y Show abstract

Cheng, I., Shariff-Marco, S., Koo, J., Monroe, K. R., Yang, J., John, E. M., Kurian, A. W., Kwan, M. L., Henderson, B. E., Bernstein, L., Lu, Y., Sposto, R., Vigen, C. L., Wu, A. H., Gomez, S. L., & Keegan, T. H. (2015). Contribution of the neighborhood environment and obesity to breast cancer survival: The California Breast Cancer Survivorship Consortium. Cancer Epidemiology, Biomarkers & Prevention, 24(8), 1282-1290. https://doi.org/10.1158/1055-9965.EPI-15-0055 Show abstract

Sequeira, P. A., Pyatak, E. A., Weigensberg, M. J., Vigen, C. P., Wood, J. R., Ruelas, V., Montoya, L., Cohen, M., Speer, H., Clark, S., & Peters, A. L. (2015). Let's Empower and Prepare (LEAP): Evaluation of a structured transition program for young adults with type 1 diabetes. Diabetes Care, 38(8), 1412-1419. https://doi.org/10.2337/dc14-2577 Show abstract

Lu, Y., John, E. M., Sullivan-Halley, J., Vigen, C. L., Gomez, S. L., Kwan, M. L., Caan, B. J., Lee, V. S., Roh, J. M., Shariff-Marco, S., Keegan, T. H., Kurian, A. W., Monroe, K. R., Cheng, I., Sposto, R., Wu, A. H., & Bernstein, L. (2015). History of recreational physical activity and survival after breast cancer: The California Breast Cancer Survivorship Consortium. American Journal of Epidemiology, 181(12), 944-955. https://doi.org/10.1093/aje/kwu466 Show abstract

Wu, A. H., Kurian, A. W., Kwan, M. L., John, E. M., Lu, Y., Keegan, T. H., Gomez, S. L., Cheng, I., Shariff-Marco, S., Caan, B. J., Lee, V. S., Sullivan-Halley, J., Tseng, C.-C., Bernstein, L., Sposto, R., & Vigen, C. L. (2015). Diabetes and other comorbidities in breast cancer survival by race/ethnicity: The California Breast Cancer Survivorship Consortium (CBCSC). Cancer Epidemiology, Biomarkers & Prevention, 24(2), 361-368. https://doi.org/10.1158/1055-9965.EPI-14-1140 Show abstract

2014

Journal Articles

Mallinson, T., Schepens Niemiec, S. L., Carlson, M., Leland, N., Vigen, C., Blanchard, J., & Clark, F. (2014). Development and validation of the activity significance personal evaluation (ASPEn) scale. Australian Occupational Therapy Journal, 61(6), 384-393. https://doi.org/10.1111/1440-1630.12155 Show abstract

Pyatak, E. A., Sequeira, P. A., Whittemore, R., Vigen, C. P., Peters, A. L., & Weigensberg, M. J. (2014). Challenges contributing to disrupted transition from paediatric to adult diabetes care in young adults with type 1 diabetes. Diabetic Medicine, 31(12), 1615-1624. https://doi.org/10.1111/dme.12485 Show abstract

Carlson, M., Jackson, J., Mandel, D., Blanchard, J., Holguin, J., Lai, M. Y., Marterella, A., Vigen, C., Gleason, S., Lam, C., Azen, S., & Clark, F. (2014). Predictors of retention among African American and Hispanic older adult research participants in the Well Elderly 2 randomized controlled trial. Journal of Applied Gerontology, 33(3), 357-382. https://doi.org/10.1177/0733464812471444 Show abstract

Clark, F., Pyatak, E. A., Carlson, M., Blanche, E. I., Vigen, C., Hay, J., Mallinson, T., Blanchard, J., Unger, J. B., Garber, S. L., Díaz, J., Floríndez, L. I., Atkins, M., Rubayi, S., & Azen, S. P. (2014). Implementing trials of complex interventions in community settings: The USC-Rancho Los Amigos Pressure Ulcer Prevention Study (PUPS). Clinical Trials, 11(2), 218-229. https://doi.org/10.1177/1740774514521904 Show abstract

Kwan, M. L., John, E. M., Caan, B. J., Lee, V. S., Bernstein, L., Cheng, I., Gomez, S. L., Henderson, B. E., Keegan, T. H., Kurian, A. W., Lu, Y., Monroe, K. R., Roh, J. M., Shariff-Marco, S., Sposto, R., Vigen, C., & Wu, A. H. (2014). Obesity and mortality after breast cancer by race/ethnicity: The California Breast Cancer Survivorship Consortium. American Journal of Epidemiology, 179(1), 95-111. https://doi.org/10.1093/aje/kwt233 Show abstract

2013

Journal Articles

Wu, A. H., Gomez, S. L., Vigen, C., Kwan, M. L., Keegan, T. H., Lu, Y., Shariff-Marco, S., Monroe, K. R., Kurian, A. W., Cheng, I., Caan, B. J., Lee, V. S., Roh, J. M., Sullivan-Halley, J., Henderson, B. E., Bernstein, L., John, E. M., & Sposto, R. (2013). The California Breast Cancer Survivorship Consortium (CBCSC): Prognostic factors associated with racial/ethnic differences in breast cancer survival. Cancer Causes & Control, 24(10), 1821-1836. https://doi.org/10.1007/s10552-013-0260-7 Show abstract

Wu, A. H., Lee, E., & Vigen, C. (2013). Soy isoflavones and breast cancer. American Society of Clinical Oncology Educational Book, 2013, 102-106. https://doi.org/10.1200/EdBook_AM.2013.33.102 Show abstract

2012

Journal Articles

Wu, A. H., Vigen, C., Razavi, P., Tseng, C. C., & Stancyzk, F. Z. (2012). Alcohol and breast cancer risk among Asian-American women in Los Angeles County. Breast Cancer Research: BCR, 14(6), R151. https://doi.org/10.1186/bcr3363 Show abstract

Baydur, A., Vigen, C., & Chen, Z. (2012). Expiratory flow limitation in obstructive sleep apnea and COPD: A quantitative method to detect pattern differences using the negative expiratory pressure technique. Open Respiratory Medicine Journal, 6, 111-120. https://doi.org/10.2174/1874306401206010111 Show abstract

Grimminger, P. P., Shi, M., Barrett, C., Lebwohl, D., Danenberg, K. D., Brabender, J., Vigen, C. L., Danenberg, P. V., Winder, T., & Lenz, H. J. (2012). TS and ERCC-1 mRNA expressions and clinical outcome in patients with metastatic colon cancer in CONFIRM-1 and -2 clinical trials. The Pharmacogenomics Journal, 12, 404-411. https://doi.org/10.1038/tpj.2011.29 Show abstract

McDonald, A. E., & Vigen, C. (2012). Reliability and validity of the McDonald Play Inventory. American Journal of Occupational Therapy, 66(4), e52-e60. https://doi.org/10.5014/ajot.2012.002493 Show abstract

2011

Journal Articles

Kim, J. S., Holtom, P., & Vigen, C. (2011). Reduction of catheter-related bloodstream infections through the use of a central venous line bundle: Epidemiologic and economic consequences. American Journal of Infection Control, 39(8), 640-646. https://doi.org/10.1016/j.ajic.2010.11.005 Show abstract

Francis, B. A., Varma, R., Vigen, C., Lai, M. Y., Winarko, J., Nguyen, B., & Azen, S. (2011). Population and high-risk group screening for glaucoma: The Los Angeles Latino Eye Study. Investigative Ophthalmology & Visual Science, 52(9), 6257-6264. https://doi.org/10.1167/iovs.09-5126 Show abstract

Vigen, C. L., Mack, W. J., Keefe, R. S., Sano, M., Sultzer, D. L., Stroup, T. S., Dagerman, K. S., Hsiao, J. K., Lebowitz, B. D., Lyketsos, C. G., Tariot, P. N., Zheng, L., & Schneider, L. S. (2011). Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: Outcomes from CATIE-AD. American Journal of Psychiatry, 168(8), 831-839. https://doi.org/10.1176/appi.ajp.2011.08121844 Show abstract

2010

Journal Articles

Salama, H., Zekri, A. R., Zern, M., Bahnassy, A., Loutfy, S., Shalaby, S., Vigen, C., Burke, W., Mostafa, M., Medhat, E., Alfi, O., & Huttinger, E. (2010). Autologous hematopoietic stem cell transplantation in 48 patients with end-stage chronic liver diseases. Cell Transplantation, 19(11), 1475-1486. https://doi.org/10.3727/096368910X514314 Show abstract

2009

Journal Articles

Zheng, L., Mack, W. J., Dagerman, K. S., Hsiao, J. S., Lebowitz, B. D., Lyketsos, C. G., Stroup, T. S., Sultzer, D. L., Tariot, P. N., Vigen, C., & Schneider, L. S. (2009). Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: The CATIE-AD study. American Journal of Psychiatry, 166(5), 583-590. https://doi.org/10.1176/appi.ajp.2008.08081218 Show abstract

2008

Journal Articles

Nowicki, M. J., Vigen, C., Mack, W. J., Seaberg, E., Landay, A., Anastos, K., Young, M., Minkoff, H., Greenblatt, R., & Levine, A. M. (2008). Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women. AIDS Research and Human Retroviruses, 24(2), 163-168. https://doi.org/10.1089/aid.2007.0119 Show abstract

2007

Journal Articles

Vigen, C., Hodis, H. N., Chandler, W. L., Lobo, R. A., & Mack, W. J. (2007). Postmenopausal oral estrogen therapy affects hemostatic factors, but does not account for reduction in the progression of subclinical atherosclerosis. Journal of Thrombosis and Haemostasis, 5(6), 1201-1208. https://doi.org/10.1111/j.1538-7836.2007.02547.x Show abstract

Anastos, K., Lu, D., Shi, Q., Tien, P. C., Kaplan, R. C., Hessol, N. A., Cole, S., Vigen, C., Cohen, M., Young, M., & Justman, J. (2007). Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens. Journal of Acquired Immune Deficiency Syndromes, 45(1), 34-42. https://doi.org/10.1097/QAI.0b013e318042d5fe Show abstract

2006

Journal Articles

O'Connell, C. L., Boswell, W. D., Duddalwar, V., Caton, A., Mark, L. S., Vigen, C., & Liebman, H. A. (2006). Unsuspected pulmonary emboli in cancer patients: Clinical correlates and relevance. Journal of Clinical Oncology, 24(30), 4928-4932. https://doi.org/10.1200/JCO.2006.06.5870 Show abstract

Levine, A. M., Vigen, C., Gravink, J., Mack, W., Watts, C. H., & Liebman, H. A. (2006). Progressive prothrombotic state in women with advancing HIV disease. Journal of Acquired Immune Deficiency Syndromes, 42(5), 572-577. https://doi.org/10.1097/01.qai.0000230320.78288.79 Show abstract

Vigen, C., Bernstein, L., & Wu, A. H. (2006). Occupational physical activity and risk of adenocarcinomas of the esophagus and stomach. International Journal of Cancer, 118(4), 1004-1009. https://doi.org/10.1002/ijc.21419 Show abstract

Andel, R., Vigen, C., Mack, W. J., Clark, L. J., & Gatz, M. (2006). The effect of education and occupational complexity on rate of cognitive decline in Alzheimer's patients. Journal of the International Neuropsychological Society, 12(1), 147-152. https://doi.org/10.1017/S1355617706060206 Show abstract

2005

Journal Articles

Vigen, C., Hodis, H. N., Selzer, R. H., Mahrer, P. R., & Mack, W. J. (2005). Relation of progression of coronary artery atherosclerosis to risk of cardiovascular events (from the Monitored Atherosclerosis Regression Study). American Journal of Cardiology, 95(11), 1277-1282. https://doi.org/10.1016/j.amjcard.2005.01.068 Show abstract