Faculty / Staff Resources Student Resources
University of Southern California
University of Southern California
USC Chan Division of Occupational Science and Occupational Therapy
USC Chan Division of Occupational Science and Occupational Therapy
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Lifestyle Redesign® for Pressure Ulcer Prevention in Spinal Cord Injury (PUPS)

Health Core ⟩ Lifestyle Interventions for Health Promotion and Prevention Lab ⟩

Principal Investigator: Florence Clark PhD, FAOTA

Collaborators (USC): Erna Blanche PhD, OTR/L, FAOTA ; Stan Azen; Joel Hay; Jennifer Unger

Collaborators (RLANRH): Salah Rubayi; Michael Scott

Sep 2008 – Jul 2014

Total funding

Advanced pressure ulcers are a common and medically serious complication of spinal cord injury (SCI) and are associated with extremely high treatment costs and reduced quality of life. However, preventive interventions that address this problem have received very little research attention. To address this gap, PUPS investigated the efficacy of a promising lifestyle intervention designed to prevent pressure ulcers among at-risk members of the SCI population. The six-year study involved collaboration between researchers from the University of Southern California (USC) and Rancho Los Amigos National Rehabilitation Center (RLANRC), who have developed the intervention based on the results of a qualitative investigation of lifestyle and ulcer risk among adults with SCI. The long-term objective of this project was the identification of an intervention option that can enhance the health and life quality of the population of adults with SCI while simultaneously diminishing the heavy healthcare burden that results from the problem of SCI-related pressure ulcers.

Division faculty members Stanley Azen and Erna Blanche were key collaborators. Additional USC collaborators included Clinical Pharmacy and Pharmaceutical Economics & Policy Professor Joel Hay, Professor of Preventive Medicine Jennifer Unger, and from Rancho Los Amigos National Rehabilitation Hospital (RLANRH), Salah Rubayi and Michael Scott.


Type Source Number Amount Period
Federal NIH / National Institute of Child Health and Human Development (NICHD) 5R01HD056267-05 $523,225 Aug 2012 – Jul 2014
Federal NIH / NICHD 5R01HD056267-04 $507,883 Aug 2011 – Jul 2012
Federal NIH / NICHD 3R01HD056267-03S1 $223,722 Aug 2010 – Sep 2011
Federal NIH / NICHD 5R01HD056267-03 $604,332 Aug 2010 – Jul 2011
Federal NIH / NICHD 5R01HD056267-02 $614,498 Aug 2009 – Jul 2010
Federal NIH / NICHD 1R01HD056267-01A1 $562,336 Sep 2008 – Jul 2009